What is the best times to take your regimen Morning and night or with the same digits say 6am and 6pm?? Suggestions please. 

I honestly can't say for sure, but I've always taken mine at 7:30 and 7:30. I take spiro both times and estradiol once. I recently moved the E to mornings when I missed a dose.

Don't worry about precise timing. In genetic females, the estradiol and progesterone levels change hugely during the menstrual cycle. It's not like diabetes where you'd need to be very careful.

Quote from: Apple on January 14, 2015, 07:31:34 AM
Don't worry about precise timing. In genetic females, the estradiol and progesterone levels change hugely during the menstrual cycle. It's not like diabetes where you'd need to be very careful.

this

I take first dose in the AM, 2nd dose before I go to bed

I take mine when I wake up, and when I get off work. E and Spiro both times.

On Spiro I generally take a dose around 5/6am in the morning and the other dose around 5/6pm at night. As others have pointed it isn't an exactly have to be the same everyday. My IM injections I generally do in the mornings.
Mariah

Ok, this is what works for me.
I take my first spiro dose and all my estrogen in the morning when i get up (7:00),
Then when i get home from work at 17:00 i have the 2nd spiro dose.
Its not perfectly 12 hours apart, but nothing is perfect... I do try and wait at least 2 hours after the 2nd spiro before consuming any alcohol so that it is at least sort of absorbed in m blood.

 Thank you so much for all of the help. It sure is a learning adventure.

6AM, 2PM and 10PM.

Morning when I get up, lunch, and bedtime.

Works for me. Seems to keep me from crashing. At one time I took all once in the morning and by mid-day I was totally miserable. Now with the divided dose I'm fine all day long.

Spiro gets taken with breakfast, around 9AM (at work) along with my other medicines.