Hi all

I am a bit worried about my rising T-levels

I have been on Spiro for 8 weeks now, but my serum testosterone levels keeps rising. I know Sprio is an testosterone antagonist and thereby blocks the effects of testosterone in the blood on the body, but is it normal for the body to react with increased testosterone production?

Here are my blood values:

SerumTestosterone ng/dL:
6 Weeks on Spiro           519
4 Weeks on Spiro           415
18 Weeks before Spiro   346

Thats an increase of 50%!

I have to consult this with my doctor in my next session, but that is not before mid May.
In the mean time i am worried about masculinization. Should i be worried?

Kind regards

It could well happen if the dose is not high enough to reduce metabolization to testosterone and if all it does is block testosterone in which case, similar to other anti-androgens that ONLY block testosterone, the levels rise (the body sensing there is not enough testosterone as it is blocked) BUT it doesn't matter because testosterone is blocked so you get decreased masculinization. This is why, in certain circumstances, measuring hormone levels might not be accurate and useful. It doesn't reflect the whole picture.