I'm not sure what you mean by 'spiritual self'. I have both my religion and my self-awareness - my soul.
I am in touch with my soul, my being, my place in the cosmos. Is that what you're referring to? My religion is separate from that.
And to answer the question - NO. Without being attached to one's soul, one's whole being, one cannot live. Period.
One may be breathing, but not truly alive. At this time, I am not longer attached my soul. Pain and sorrow have severed me.
I am breathing, but not living.