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An alternate to actual ERT are herbs and spices and foods that provide phyto-estrogen or enhance phyto-estrogen (e.g., soy, rosemary, black cohosh, squaw vine, yam / sweet potato, egg white, fennel). A herbalist or herbologist can help you understand the pro and con of this. I was off meds for 13 months last year and this year and, with only phyto-e, I maintained estrogen levels in the post-menopausal range (+40) - normal for me at age 59 anyway. I'm back on ERT since March (estradiol per day) and my labs showed estrogen in the normal adult female range (280)
Christine Jorgensen died in 1989 (age 62) with active breast cancer. I do not know if her breast cancer caused her death, though she did die of cancer; I just don't know if cause of death was breast cancer, or another cancer, or another cancer related to her ERT.
If you are a cancer risk, be conscientious and perform regular breast self-examination so you know what you are supposed to feel like - every woman is different in her own way. Mammograms are not painfull - the radiologist simply takes a 'photograph' of your breast tissue. You probably will get one at the end of your first year ERT as your baseline scan.
Realise exactly what you wrote - now that you will be female, all your anatomical systems will be female and susceptible to all the same issues as any other female - good, bad, indifferent.
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Mod Edit- No dosages please. TOS 8