I've been somewhat fortunate. My dysphoria gets really bad when I cannot (or perceive that I cannot) transition. I've been lucky enough to get help of my family but there was a point last year where I looked at myself and the dysphoria was worse than ever, despite having forced out about 18 months prior due to extreme dysphoria. But a lot was going on in my life as far as my finances went, I went into debt (school only) for the first time in my life, my job wasn't paying much, and I had 2 healthcare plans that covered nothing and next to nothing for transpeople. Luckily at that point I decided to pull the trigger and bank some sperm so that I could finally pop the bottle of my pills which had been sitting on my dresser for months.
That was the severe stuff. Since starting hormones, It's been nothing or the extremely light stuff triggered by sometimes feeling that every second till I become female is wasted time, the lasers working a little too slowly for my liking, and the same with the hormones as well.