I haven't noticed the coffee so much (we are all dedicated coffee drinkers here in Australia with some of the best coffee makers in the world), but I have noticed a remarkably different change in my ability to drink alcohol. I could easily drink beer (Now I don't touch the stuff) and used to like Gin and tonic or vodka and coke. I also love my wine, with my favourites Sauvignon Blanc, Chardonnay or Shiraz, but whereas before I could drink 3 or 4 glasses, since I have ben on HRT (now 2 years plus), I can manage two glasses only before its time NOT to drive home, as the alcohol definitely affects me more.