At the end of the day, it's silly and campy and I don't think taking it too seriously or overthinking this at this point is necessary. At the end of the day, Richard O'Brien can do whatever they want with reimagining it, which is what is actually happening here. (Richard O'Brien has been on HRT for at least the last decade and ID's as non-binary, BTW.) I won't knock it until I've seen it, but I think they're going to tweak the role of Frank N' Furter just a wee bit.
I'd also love to see Jack Black as Eddie...