Here are some hints concerning phytoestrogen, which might compete with estrogen for receptors, making for a weaker effect:
https://www.susans.org/forums/index.php/topic,190328.msg1695279.html#msg1695279normal amounts from time to time should be ok... I'd avoid large amounts...
avoiding soy and soy products should not be too difficult.. in the link above are some recipes given.
Pasta, bread, salads, soups are all alternatives, which can be very tasty if made by yourself. its also easy to make...
you might think about adding bioidentical progesterone to compliment estrogen.
It has some anti androgen effects, might help with mood, even out some side effects of estrogen and might help with breast development. Non bioidentical progesterone does not have these effects.
https://www.susans.org/forums/index.php/topic,192953.msg1733564.html#msg1733564it helps against dht, a strong version of testosterone which might prevent some feminization...
Now concerning injections many people switch to weekly injections.
With biweekly there is a low the last few days, which as you say may make for a menopause like effect.
I also can effect mood.
Well there is even one form of hrt with injections and implants where the levels of estrogen are driven well into the female range, above 200-300, and the t levels are driven down as well, without further anti androgen.
If your doc might look this up, they may find that there are very few studies showing higher risks with internal application and bioidentical estrogen.
Most risks like clots come from oral application. Here it is possible to switch to bioidentical micronized estrogen, dissolved sublingually to lessen the strain on the liver and also to lessen clotting factors. Part of the intake bypasses the liver by sublingual intake.
You might also think about spreading the daily dose in a few small parts. This way levels are more even.
hugs