I started while in college and am still in, and it has affected my performance. I was living with my now ex-boyfriend at the end of last year all the way up until three months ago. We started having problems during my fall semester last year and it caused me to fail half my courses and that snowballed into more problems which I've only recently sorted out. I'm currently attending now, and have a full load, and it's stressful... I'm very emotional (and my e-levels are on the high side which I'm sure is contributing to that) and I don't handle stress well anyway. It's all about how you can deal with things like that. I often resort to my vices to help me focus, de-stress, and shut my brain up a bit. So it can be hard if you haven't learned to cope with things. Transitioning in itself can be stressful and emotional, so if you add school on top of that, and then relationship stuff, it has the potential of being overwhelming. I mean, I'm two years in and staying out of relationships for now and ehh.. drinking and smoking a bit more than I should, but it's all helped and I have a handle on it all enough that I'm getting pretty good grades. I would recommend starting slow if you're going to do it.