There's so much you don't mention.
You say you came out to your wife ten years ago, but she "confronted you" with your female clothing, with one of your children!
Did you tell her you were a transvestite, when you came out to your wife, or did you tell her you were transgender? What was her reaction? Did you make some kind of deal, promising "not to do it again"?
If so, you're much to blame here. If not, then your wife is really out of bounds, especially involving one of your children. That was totally inappropriate. A wife and husband should deal with issues such as this as two adults, and not bring children into it to create emotionally-loaded scenes that are difficult to mitigate.
So does your wife know you are pursuing transition - seeing a therapist and endocrinologist?
I'm sorry, dear, that I am giving you the third degree. To answer your question, yes, spiro will help, but you need to start taking low dose estrogen for your health. Having little or no sex hormones of some kind in your body is a bad thing. The physical signs of low-dose estrogen will be minimal. Your libido will be gone, but it sounds like that is not a problem. But it will stop the dysphoria, and help your peace of mind.
By the way, I am 58, with a wife and two kids of my own, so I can relate to your situation. The only difference is I am separated. But I didn't have any marital relations with my wife for a good two years before we separated, for some of the reasons you describe. I am taking spiro, Proscar, and transdermal estradiol. Yes, the spiro has much more effect than Proscar as far as feminization, in my opinion. You can get some gynecomastia from spiro.
With kindness,
Terri