It has been a week now since my I started my raised dosage. So far, the side effects are only a lil more intense. I know this is coincidence, but on the day I started the higher dosage, I noticed the beginning of breast tenderness. Yay! I have also noticed some weight loss since I first started HRT a month ago.However that could be due to dropping from 3 sodas a day to practically no soda. I drink a LOT of water, but I use the powdered flavorings. I hate straight water. Blahhh.