Wow, you have a lot going on. My buddy had high blood pressure and is bipolar, but he was able to transition. And I know a lot of guys whose emotional problems--depression, anxiety, anger management--have improved drastically. Cholesterol, on the other hand, is likely to go up. And most FTMs' doctors are concerned about liver function and run tests periodically to make sure that everything is okay. Existing liver issues might be exacerbated. And diabetes and kidney problems, yikes.
You have a tougher road than most of us, that's for sure.