I do find the 'pill' question interesting whenever it crops up. There's not a day that goes by that I do not wish that I had been born female (and, increasingly, fighting the urges to take steps on the path to womanhood). However, till the day I die, I will always feel guilty about the hurt I caused to my wife through my confession after 20+ years of marriage and, whilst our marriage has suffered enourmously (and quite possibly irreperably) as a result. So, would I take the pill? Absolutely.
I think a more telling question to ask is to consider that there are two pills and your only choice is to take one or other - you cannot opt out of taking either. The first pill is as described in this thread - it restores your mind to match your birth gender and expunges all thoughts of transition, ->-bleeped-<- etc. The second pill changes your body but leaves your mind unaffected. I know this goes against the grain of non-binary gender etc. but I find it a far more challenging decision to consider and, in all honesty, I'm not sure which I would take.
Amanda