I suppose using church arguments to argue with church goers is one idea.
Of course that presupposes that "God" is sitting there deciding who will be born, as though rolling out new babies in magic clay dough, zapping them supernaturally with traits, and there is NO science, human will, or nature involved.
That also presupposes that "God" is controlling everything and we are just passive pawns. All birth defects, lethal problems, child abuse, environmental contamination, etc are all ordained of "God." We have zero responsibility for our lives.
With that logic, then nothing we do matters..it's all fate, under God's control.
If so, a transgender person is obviously what "God" wanted and magically made.
You could talk science, but religious people often repeat what their churches teach, without question.
Actually, Jesus said and did the opposite of that teaching. He healed people, so apparently, sickness WASN'T "God's will," he told people who were healed that their own faith healed them. He said anyone could tell a mountain to move and throw itself in the ocean and it must obey them. He scolded his disciples for waking him up to stop a storm that was sinking their boat, asking why they didn't do it themselves. Jesus was all about personal responsibility and our own God authority.