13 yrs on HRT and here are my observations:
when E is high enough: I feel VERY stable emotionally, nothing bothers me, I'm CALM. Not only that, but I have energy, feel good and SEXY/confident. Libido also goes up. Skin also becomes quite soft.
low E: I feel anxious, irritable, sleepy/tired, always hungry, not good about myself.
P tends to oppose E so I find that, although for about 1 hour, it makes me feel VERY good (due to sedative effect), it makes me cranky, feel awful afterwards, crave foods, etc...same as when I have low E.