I started with quite a large very thin patch on top and a small amount of receding at the front, I was prescribed finasteride before HRT I took that on its own for about 3 months, then I started estrodiol, and cyproterone acetate, took that for two months and had not noticed any significant changes to hair growth, I then started using minoxidil and after two months I have seen significant regrowth. I think the combination I'm on has done the trick for me, but I guess everyone reacts differently, or the sequence of medications was just right, I'm not sure. Hope this helps