I would probably post this one in the Hormone Therapy section, but in answer to your question... Yes and no. Provided you aren't zinc deficient, then the answer is "No it will not create Estrogen". If you are zinc deficent, have enough of the enzymes produced naturally, and the stars align.. then its a foggy maybe. I would doubt that the estrogen produced would be any significant level. I would suspect that raising T levels from androgel would combat any benefit from an estrogen suppliment, and could cause some health issues. Usually Estrogen is used to supress testosterone, raising testosterone sounds counterproductive. Testosterone is what inhibits males from developing breasts, because even males produce small amounts of estrogen naturally.