Do any of you all get occasional bumps from the heart when your estrogen (estradiol) is running low (like, time for another shot, etc) or when you apply progesterone? My Doctor says progesterone causes a "simulated" sudden reduction in estradiol. So, either that or ACTUAL lowering of estradiol because it is time for another shot or pellets. I understand MOST people only feel anxiety, night sweats, and things like that. I do NOT get any of those but the heart starts getting a bit sh-ty... AND, ONLY at NIGHT. (Now why in hell is that...) My Doctor says that apparently, the "chemical anxiety" that lowering estradiol causes apparently all goes to my heart rather than those more common symptoms. I wish I would just have the night sweats, general anxiety and stuff. I have ways of coping with those. But I HATE heart bumps. (Note, I add progesterone as transdermal cream because it helps with breast growth and increases energy. But... I guess I better not do it... dammit)