I haven't been a big drinker since I was in my 20s. These days, I seldom have more than one drink, and that is not very often. Two is my absolute limit, and I don't even remember the last time I had two. If you drink less, you lose your tolerance. One glass of wine will give me quite a buzz these days.
I don't really notice a difference before and after HRT.
Estradiol is hard on the liver when taken orally. I use a patch, so it should be safer, but I don't feel like stressing my liver more than necessary. If I wasn't already a light drinker, I would have cut back when I started HRT.