I've been on HRT for almost two and a half years. I was started on a very low dosage of Premarin, at the same time as spiro. A few months later I was switched to a higher dosage of Estrace pills, which was a noticeable improvement, and the Estrace dosage was increased a few more times over the course of the following year. But I still craved more. More. MORE. I've never loved anything so much. I savor it. I kept bugging my endocrinologist for a stronger dose.
So last week I stopped taking pills and started injecting Delestrogen. Whoa this stuff rocks. One lady I know told me her breast size doubled within a few months after she switched from pills to patches. My one trans friend who knows a lot about medication told me that injecting it is even better than patches. Within a couple of days after my first shot, my breasts and nipples started growing noticeably bigger and have become so sensitive, just the feeling of my cotton nightie lightly brushing over them has been driving me out of my mind. Good times.

I have great hopes for injected Delestrogen, based on just this one shot. As a bonus it should give my liver a break, as has been mentioned above. Now I regret having wasted years on taking pills when I could have been shooting up.*
You have to inject it into the muscle of the upper outer quadrant of the gluteal area. There is a rather specific area there to aim for where you hit muscle instead of fat. I recommend consulting an anatomy textbook.

*"One pill (estro) makes you larger (breasts), and the other one (spiro) makes you small (nuts & prostate). And the ones your endocrinologist prescribes for you don't do anything at all."
Changed title back to Re: "Holler!! Im about to start estrogen", please review the site rules/TOS, rule #11 regarding language, thanks - Tink