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New insights into SRY regulation through identification of 5' conserved sequence

Started by Natasha, October 14, 2008, 05:38:06 PM

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Natasha

October 14, 2008, 05:38:06 PM
New insights into SRY regulation through identification of 5' conserved sequences

http://7thspace.com/headlines/295176/new_insights_into_sry_regulation_through_identification_of_5_conserved_sequences.html
10/14/2008

SRY is the pivotal gene initiating male sex determination in most mammals, but how its expression is regulated is still not understood. In this study we derived novel SRY 5' flanking genomic sequence data from bovine and caprine genomic BAC clones.
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Seshatneferw

#2
November 12, 2008, 04:31:25 AM
Very roughly, the SRY gene (a small segment of the Y chromosome) is the 'master switch' regarding sex. This study has identified a few other gene sequences that have something to do with determining what happens when that master switch is flipped from 'female' to 'male'. They also suggest that mutations in these might have something to do with intersex conditions where a woman has a Y chromosome.

  Nfr
Whoopee! Man, that may have been a small one for Neil, but it's a long one for me.
-- Pete Conrad, Apollo XII
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iFindMeHere

#3
November 12, 2008, 09:03:20 AM
thank you for the crayon edition. Now I understand it. :)
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