OK, here is the insight - or if not insight, at least the facts where the rubber meets the road of reality.
It's as ridiculous as finding a real deaf woman for Children of a Lesser God,
Yeah, and of course, they could have gone, as they did for CoaLG to the trans equivalent of the International Center On Deafness and the Arts, or the National Theater of the Deaf that exist to train and support deaf actors. Yeah, what's the name of that Trans acting group again? Oh yeah, there isn't one. And of course, if there were such a group, like the ICODA or NTotD for trans persons you all would heavily support it wouldn't you? Just like the deaf population has organized and supports those groups.
Of course you wouldn't. My god, most of you are afraid to have your cover blown by just being around one transperson, much less a huge public display of them.
And, as good as those groups are, and NTotD is mind blowing good, and amazingly funny, they have succeeded in getting one, count them one, person into the mainstream.
Good actors - and I use the theatrical preference of a single word, non-gendered, for both male and females of the acting persuasion - can convince you of just about anything (which is why you never marry them). On a rare occasion you do get someone who really is that person. Errol Flynn was such a guy, a movie tough guy, pirate captain, extremely romantic lead who really could, and did, and loved doing it, kick major ass in a bar fight while drinking heavily and doing lots of drugs and have sex (lots of it) with teenagers while sailing his yacht the Scirocco across the Pacific. (Hence the phrase, In Like Flynn) But most movie tough guys are like Clint Eastwood, mild mannered, serious professionals who only play the part when the cameras are running.
And it's the whole cameras running deal that causes the problem. Time is money, and in no place is that truer than in making movies. Every second is the cost of the crew (large) and the rental of the equipment (also huge), plus the cost of the film and developing (ball park is $300-400 per minute, per camera) - not to mention the enormous post production costs - as well as the other costs like accounts, lawyers and cooks/craft service people that has to be paid in full, upfront, before a single penny of revenue comes in.
So that, currently, the average cost of a Hollywood movie (and we're talking average, not huge productions) is now right around $106 million dollars.
Who exactly, even in la-la land Hollywood is going to fork over $106 million dollars on something that was unproven? Now, TransAmerica was a low budget, independent film. No doubt a bargain at the mere $1 million it cost to produce.
So, who's got a spare million bucks that they can risk (and make no mistake about it, financing a film is pretty much the equivalent of taking that million bucks down to the track and betting the trifecta) on making a movie about a subject of marginal interest with unknown persons as actors? Any takers? Of course not, I read the posts here, half of you are having a hard time making rent, much less tossing around a million bucks.
Now TransAmerica made about $8 million, which was enough to cover the costs, pay back the investors, and maybe make a bit on the side. And why was that? As most of the people above have said, it wasn't an awesome movie, but Felicity Huffman (and a few other people in it) did fantastic performances that at least got the film buffs out to see it. If you go to the IMDB 90% of what is written about the movie in the 200+ comments is all about Felicity's acting job. Without her, the movie goes nowhere. Ever. And Felicity Huffman also was in at that time some TV series that was doing well, so that got some people to at least notice it.
If your good at your craft, you don't have to really be that person (method acting aside). Anthony Hopkins in real life is a perfect British gentleman, not not that evil, almost a delicious evil, as his character is in Silence of the Lambs. Though, by all accounts, Jodi Foster is very close to being Clarice Starling, minus the self-doubt. For sure many male romantic leads that make all sorts of girls squirm in their seats and get all wet were very, very gay, or at least very bi, in real life, like Montgomery Clift or James Dean.
And anymore you don't even have to be male to play a male lead, even of a very famous male. Watch I'm Not There and though most of it sucks, Cate Blanchett playing the circa mid-60s drug addled Bob is perhaps one of the great film portrayals ever. Like Felicity, she was robbed - hell she was outright mugged - by the Academy.