I think we are a pretty funny bunch. I laugh at myself a lot.
The question I would think about it whether the funny stuff was balanced by some realistic depictions in media. As long as it is not done in a derogetory way (just look at british comedy - it is loaded with queer references which I don't think are derogetory at all, just a culturaly acceptable way to talk about queer people).
I can think of heaps of shows and cartoons where being gay is ok - e.g. Ugly Betty, Telly Tubbies, Skins, Eddie Izzard, Simpsons, Americas next top model, queer eye for the straight guy, L word, family guy, American dad..to name a few.
What we don't see a lot of is transgender stuff, but I think it is on the rise.