I'm sort of odd here. I'm good at things that require spatial reasoning (I'm a math/geophysics major, spent 5 years in the Navy as an aircraft structural mechanic, play videogames, can outnavigate almost anyone) but I don't seem to do them in the same way as other people who are good at them do. My spacial visualization is nonexistent; I rely a lot on verbal reasoning and intuition.
I can't tell left from right, can't read a clock, and on those 3-d block rotation puzzles I can't even begin to "see" the block turning in my head...but dammit, I just know that place we're looking for is right over thataway about 3 blocks and up the hill, this part goes in this space if you turn it just so and slide it between these fuel lines, and block C is the only one that could possibly be the same as the original. Don't ask why, just do it, you'll see I'm right.
So my brain works kind of funny to begin with. Can't say I've noticed hormones making a difference in my spatial skill. I have noticed other things, like I actually have visual dreams now (I used to think my entire visual imagination function was broken) but I'm not any better at math or map reading or any of that. I suspect most of that is fixed by adulthood.