I haven't had any allergy problems with my silicone packer (pierre). I have had problems with cyberskin - not because I'm allergic to the material itself, but mostly because it picks up dust and who knows what else and I find it difficult to keep clean. And that is what irritates my skin. At any rate, I don't wear it up against my skin anymore because it gives me a rash. I drop it into a jock (which I wash regularly).