I've had ocassional major doubts.
I've contemplated stopping transition two times since I've started it. Those times I would consider it some occasional major doubts, if you ask me.
The problem for me when I first started transitioning, was that like I thought that I will/could never live a normal life if I chose this path. That I would always be some man CDing fulltime or something. To this day I still do believe that somewhat, but really, I don't know why, but I can put it behind me easier now.
The first time I stopped transition for like 4 days, what a successful attempt huh? lol. I just got sick of having to be this one dumb person that had to deal with this, and I didn't want to deal with it. Like, on one end of the spectrum, I wanted to jump in this and get going, then when I did I wanted to fight it and stop and live happily as a guy.
I have a couple pretty major indecisions during transition, but overall, I kept going and just kept hoping for a happier day. And as of right now, even though the whole deal with hormones/transition is dragging it's feet with me, at least I'm happy and content to some extent. I still have a lot of stuff to work through, but at least I can tell myself what I'm doing is right, and I don't want to look back anymore. Sure, everyone has bad days, but I mean they keep getting more scarce the further you go it seems; for me at least.