I have the same issue with my one grandmother. Her way of "coping" with my transition is to pretend it doesn't exist. She won't acknowledge it in any way, shape, or form. It's been almost half a year on T and she doesn't know because she shut me out so much that there's never been an opportunity to properly discuss it. So, uh. Yeah. I'm just going to cross that bridge when I get there because it isn't worth the stress if she won't acknowledge me anyway.
What made me unhappy is that out of literally NOWHERE my body began to ache like nothing else. I am sore all over and it's making me feel a little nauseated.