Susan's Place Logo

News:

Based on internal web log processing I show 3,417,511 Users made 5,324,115 Visits Accounting for 199,729,420 pageviews and 8.954.49 TB of data transfer for 2017, all on a little over $2,000 per month.

Help support this website by Donating or Subscribing! (Updated)

Main Menu

Severe negative impact in mood/mental state when on micronized progesterone...

Started by Pipes, October 04, 2016, 04:46:07 PM

Previous topic - Next topic

0 Members and 1 Guest are viewing this topic.

Pipes

I have been on HRT for ~1 year consisting of the usual transdermal Estradiol & oral Spironolactone.

I had read a lot about the potential benefits of adding progesterone to my regimen and asked my endo about it.

After much discussion I was able to receive an RX for medroxyprogesterone but was told I would not be able to get the micronized progesterone unless I had a bad reaction from the medroxyprogesterone.

I tried the medroxyprogesterone for 3 cycles that consisted of 2 weeks on, 2 weeks off.

During the first cycle I did notice a depressant impact but it wasn't huge or debilitating.

During the following two cycles I did NOT notice a measurable depressant effect.

--

I had read quite a bit about the potential benefits of micronized progesterone as compared to the medroxyprogesterone and was eventually able to get my endo to prescribe it to replace the medroxyprogesterone.

I tried the new micronized progesterone and only lasted 5 days before I had to stop.

I was heavily effected by an increasingly depressive effects that by day 5 had me unable to leave the house and missing work.

This is not normal for me at all, I haven't missed a day of work since starting HRT due to depression/gender dysphoria.

I stopped taking it on the 5th day and within 36 hours felt much much better, back to my former self.

--

So, I am wondering if anyone else has had similar results and wanted to post this as a warning to anyone else considering adding progesterone to their regimen.
  •  

Angélique LaCava

I've been on medoxyprogesterone for 4 months and I'm happy with it. Haven't had any negative side affects.
  •  

Doreen

Medroxyprogesterone did absolutely nothing for me to be honest... I started micronized progesterone, and have noticed a WORLD of difference.   It could be just my personal biology, but really my breasts have grown dramatically on it.  I'm post , been on hormones over a decade... recently micro-p in the last couple months. 
  •