There were 1,5 years between my girlfriend telling her parents, and her parents accepting her for who she was so she could start taking hormones. This was when she was still a teenager, almost a decade ago now. During those 1,5 years, her life was very difficult, as her parents tried everything to keep her from being who she was, going as far as saying things as 'you're just an effimate boy' and 'you can be whatever you want to be inside the house, as long as you keep up your male appearance and personae [the 'facade'] to the outside world'. This worst thing they said, was that, and I quote 'nobody will want you for what you are. You will be alone for the rest of your life if you transition'.
They were basically more concerned with what the 'outside world' would think than with the well-being of their own daughter. Things have much improved since then, but she's never forgiven them for this. Nor should se.
She had a very severe depression because of this, which eventually became suïcidal. She could not be who she was, having to put up a facade all the time. The people who were the closest to her, the only people she had, who she relied on for support, did not understand her, turned her away. They kept her from being herself by actively trying to dissuade her, as they had to give their consent for the transition (she was still underage at the time). Things led from bad to worse. She never did drugs, or knives, or anything of the sort, just getting more and more depressed every day. She started wondering if it made any difference if she were dead. The answer she got back from herself was 'no'.
Eventually, one day, as she was staying in her parent's 10th story appartment, she walked out to the edge of the balcony, looked down and was about to jump. She just didn't care anymore. She stood there for ten minutes, which seemed like an eternity. Eventually though, she turned back. She didn't want it to end that way, there and then.
The week after that, after she'd told her parents about her near-suïcide, they realised how much it meant for her, finally accepted her. Things have gotten much better since. She got out of her depression, transitioned with HRT and SRS.
Now, she can't imagine what it was like, being in that depressed state. But she can still very vividly recall that moment, standing at the edge of the cliff, looking down into oblivion. For her, it was a turning point in her life.